Ingredient · Sleep
Apigenin
The calming flavonoid found in chamomile — studied for relaxation and sleep quality.
Apigenin is a plant flavonoid found in chamomile, parsley, and celery. It's the compound most often credited for the calming effect of a cup of chamomile tea — except a single cup contains only a trace amount. Supplementing gives you a consistent, measurable dose.
What it is
Apigenin is a naturally occurring 4',5,7-trihydroxyflavone. We use a purified apigenin rather than a chamomile extract, so the active dose is known and repeatable instead of varying batch to batch with the plant material.
How it works
Apigenin binds to benzodiazepine sites on the GABA-A receptor with mild affinity, nudging the nervous system toward its rest state without the sedation or dependence profile of pharmaceutical sleep aids. It also acts as an antioxidant and has been studied for its effect on sleep continuity — how well you stay asleep, not just how fast you fall asleep.
Studied dose
25–100 mg taken 30–60 minutes before bed
SumCo's dose
50 mg per gummy
Products with Apigenin
Further reading
Ingredients · 6 min
Apigenin for sleep: what it is, how much, and how it compares to melatonin.
The calming flavonoid behind chamomile tea — and why we put 50mg of it next to a low melatonin dose instead of raising the melatonin.
Ingredients · 6 min
Magnesium citrate vs glycinate: which one for sleep and relaxation?
Two of the most recommended magnesium forms, compared honestly — including the trade-off nobody mentions.
Other ingredients
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.